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Excessive salt consumption appears to be bad for your bones

A high-salt diet raises a woman's risk of breaking a bone after menopause, no matter what her bone density is, according to a new study that will be presented Saturday at The Endocrine Society's 95th...

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Not only bone density, but also quality of bone predicts fracture risk

In a study carried out at the University of Eastern Finland, bone histomorphometry and infrared spectroscopy revealed abnormal bone properties in children with vertebral fractures and in children after...

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A step toward clarification of the mechanisms of osteoporosis

In the bones supporting our bodies, calcium regulation occurs by balancing the activities of osteoclasts, which are groups of cells that increase the calcium concentration in blood by destroying bone...

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Researchers use calcium isotope analysis to predict myeloma progression

A team of researchers from Arizona State University and Mayo Clinic is showing how a staple of Earth science research can be used in biomedical settings to predict the course of disease.

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Sleep problems may impact bone health

The daily rhythm of bone turnover is likely important for normal bone health, and recent research suggests that sleep apnea may be an unrecognized cause of some cases of osteoporosis. Sleep apnea's...

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High-value research of 2014 presented for endocrinology

(HealthDay)—Articles relating to diabetes and obesity, lipid management, bone metabolism, adrenal disorders, and thyroid disorders are included in a special endocrinology update summary published...

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New, 'robust' treatment for stroke uses genetic material from bone marrow

In the latest in a series of experiments testing the use of stem cells to treat neurological disease, researchers at Henry Ford Hospital have shown for the first time that microscopic material in the...

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New research supports intentional weight loss for older adults

The medical community touts the importance of not carrying excess weight, but that has not always been the message delivered to older adults.

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Risk of osteoporosis drug's side effects not significant, researchers find

The risks of developing kidney failure and a calcium deficiency from the popular osteoporosis drug zoledronic acid are extremely rare, according to researchers at Loyola University Health System...

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Researchers discover exactly how calcium phosphate can coax stem cells to...

With the help of biomimetic matrices, a research team led by bioengineers at the University of California, San Diego has discovered exactly how calcium phosphate can coax stem cells to become...

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Vimizim approved for rare childhood disorder

(HealthDay)—Vimizim (elosulfase alfa) has been approved by the U.S. Food and Drug Administration to treat a rare childhood disorder called Mucopolysaccharidosis Type IVA, also known as Morquio A syndrome.

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Discovery could lead to new cancer treatment

A team of scientists from the University of Colorado School of Medicine has reported the breakthrough discovery of a process to expand production of stem cells used to treat cancer patients. These...

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Resveratrol boosts spinal bone density in men with metabolic syndrome

Resveratrol, a natural compound found in red wine and grapes, increased spinal bone density in men with metabolic syndrome and could hold promise as a treatment for osteoporosis, according to a new...

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Can our bones protect us against diabetes and obesity?

A team of researchers at the IRCM led by Mathieu Ferron, PhD, in collaboration with researchers at Columbia University, discovered a new function of the skeleton associated with diabetes and obesity....

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Study: Calcium supplementation does not clog arteries

Contrary to recent reports, consuming calcium supplements is not likely to cause heart problems or heart attacks, according to a study from Purdue University.

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Of brains and bones: How hunger neurons control bone mass

In an advance that helps clarify the role of a cluster of neurons in the brain, Yale School of Medicine researchers have found that these neurons not only control hunger and appetite, but also regulate...

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Gene therapy could aid weight loss without affecting bone loss

Delivering the hormone leptin directly to the brain through gene therapy aids weight loss without the significant side effect of bone loss, according to new collaborative research from Oregon State...

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Better survival of implanted cells improves healing of bone fractures

To treat a complicated, non-healing bone defect, surgeons often use an implant with living cells to promote bone repair, but the implanted cells have a small chance of surviving because they are not...

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Almost one third of infertile men at increased risk of metabolic diseases as...

Men with fertility problems are at increased risk of metabolic diseases as they age, according to work being presented at the European Association of Urology conference in Munich.

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Osteoporosis: Antibody crystallized

Inhibiting a protein called Sclerostin could probably help treating the bone-loss disease osteoporosis. New findings at the University of Würzburg could stimulate this research.

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Understanding the fascinating interaction between bone and brain

"The best news is that the brain has become front and centre in the regulation of bone modelling", conclude authors Professors Paul Dimitri and Cliff Rosen in their concise review of the complex role...

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Generating brown fat cells from bone marrow-derived stem cells could...

A renewable source of brown fat cells, and a simple method for generating them in cell cultures, has been discovered by A*STAR researchers and could help with the development of personalized therapies...

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Diabetes drug metformin corrects mitochondrial metabolism in familial cancer...

Individuals with Li-Fraumeni syndrome are at an increased risk for a number of cancers, including breast and bone cancer. Li-Fraumeni syndrome is an inherited cancer disorder caused by mutations in the...

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Exercise-induced hormone irisin linked to new mechanisms for bone metabolism

Two weeks of voluntary wheel running induces higher expression of irisin—a fat-burning hormone that is released during exercise—in bone tissue in mice. In addition, systemic administration of irisin...

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Bone, basal metabolism link depends on vitamin D level

(HealthDay)—For postmenopausal women with type 2 diabetes mellitus (T2DMPW), the correlation between bone metabolism and basal metabolism seems to be dependent on serum 25-hydroxyvitamin D (25[OH]D)...

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Researchers recommend specific diabetes medications to protect bone health

Type 2 diabetes (T2D) and osteoporosis often coexist in patients, but managing both conditions can be a challenge. A comprehensive review published in the Endocrine Society's Journal of Clinical...

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Researchers identify promising target to protect bone in patients with diabetes

Utilizing metabolomics research techniques, NYU Dentistry researchers investigated the underlying biochemical activity and signaling within the bone marrow of hyperglycemic mice with hopes of reducing...

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Study identifies multiple roles of glucose metabolism in platelet activation...

Platelets, the cells in blood that enable clotting, are highly reliant on their ability to metabolize glucose, according to a new study by researchers at the University of Iowa.

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Weight loss surgery's effects on bone marrow fat and bone mass

Bone marrow fat is thought to regulate bone metabolism, and high levels of marrow fat are seen in states of low bone mass, severe underweight, and diabetes. In a study of obese women undergoing gastric...

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Depression, anxiety may affect bone metabolism in older teens

(HealthDay)—Major depressive disorder (MDD), generalized anxiety disorder (GAD), and selective serotonin reuptake inhibitor (SSRI) use are associated with bone metabolism in older adolescents and young...

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